After that, Addison Bryce lived a very comfortable life. The seniors in the laboratory were very enthusiastic. Whenever he encountered a problem, they would always take the initiative to help him, and he had a very harmonious relationship with everyone.
When he was not in the laboratory on weekdays, Addison Bryce would usually go around the school with Qin Wei. However, he was not in a hurry to confirm his relationship with Qin Wei. After all, it was more appropriate to take things step by step for a relationship.
At the same time, he also took the time to register the relevant patents for the single-base gene editing technology. Although this technology is not the kind of magical black technology that transcends the times, it is necessary to register the patent first in order to better protect its own rights and interests.
At eight o'clock that night, in the laboratory.
"Addison, see you tomorrow." A senior took off his scientific research suit and said goodbye to Addison Bryce.
"See you tomorrow." Addison Bryce responded with a smile, and then continued to observe the cells in the culture dish with the help of a micromanipulator.
At this moment, he is conducting an experiment on single-base gene editing technology. The material used in the experiment is the blood of a cancer patient. He plans to extract immune cells from the blood sample, and then use single-base gene editing technology to inactivate the gene encoding PD-1 protein in the immune cells.
PD-1 is the programmed death receptor on the surface of immune cells. Once it binds to the ligand PD-L1 on cancer cells, it will hinder the killing effect of immune cells on cancer cells. If this experiment is successful, just inject the gene-edited cells into the patient's body to enhance the killing power of the patient's immune cells against cancer cells, thereby benefiting cancer patients.
"It's really troublesome to do these experiments in the laboratory." Addison Bryce sighed softly.
With the help of the gene evolution system, he can perfectly control the cells in his body, and even perform precise atomic-level operations on any substance in the cell. Modifying genes is even easier for him. However, using the existing instruments in the laboratory to do experiments is much more complicated. Existing instruments cannot directly operate genes accurately, and special methods must be used. The single-base gene editing technology he constructed is one of them.
"Alas, it's not the fault of the current instruments. It's mainly because my 'plug-in' is too powerful." Addison Bryce smiled again and continued to experiment.
After a whole night of focused research, it was soon dawn.
Johnson walked into the laboratory in a scientific research suit and saw Addison Bryce. He asked with concern: "You didn't rest last night and kept doing experiments?"
"The experiment has reached a critical stage, and I have to keep watching. Fortunately, the experiment was successful." Addison Bryce smiled brightly, picked up an experimental data report and handed it to Johnson, saying, "I used single-base gene editing technology to successfully inactivate the gene responsible for encoding PD-1 protein in immune cells, and the off-target rate is very low, only 1.3%."
The so-called off-target refers to the misoperation of other genes during the editing process. For example, if you originally wanted to edit gene A, but edited gene B instead, there is a serious safety risk. The current mainstream CRISPR-Cas9 gene editing technology has a high off-target problem, which is also the key factor that has delayed its commercialization.
"Let me see!" Johnson excitedly took the document handed over by Addison Bryce and read it carefully. The more he read, the happier he was, and a bright smile gradually appeared on his face.
"Sure enough, as I judged, the single-base gene editing technology you invented is at least ten times more advanced than CRISPR-Cas9 gene editing technology. With this technology, the field of gene editing technology is about to enter a new era. However, these data are not sufficient. You can do a few more experiments, collect more data, and then you can start writing a paper. After writing, I will help you check it and then submit it to the magazine "Cell". " Johnson said excitedly.
Addison Bryce nodded, didn't take time to rest, hurriedly ate something, and then continued to devote himself to the experiment. He was busy until the afternoon. He completed four more experiments and carefully recorded the experimental data.
"It's perfect!" Johnson, who had been observing and guiding from the side, couldn't help but slap his thigh and shouted excitedly when he saw these data. He felt more and more that being able to accept Addison Bryce as a student might be the proudest thing in his life. This student is simply a genius beyond imagination!
"Wow, so awesome!"
"Addison, from now on, you are my idol!"
"From these experimental data, single-base gene editing technology is more advanced than CRISPR-Cas9 gene editing technology in all aspects, and it can completely replace it! Oh my God! There will be a big earthquake in the biological world!"
"Addison will be my capital for showing off in the future."
Others who have been observing from the side couldn't help cheering at this moment. They looked at Addison Bryce with envy and respect, as if they saw a superstar in the biological world slowly rising.
As for jealousy, it doesn't exist. Jealousy only occurs when the gap is small, and when the gap is large to a certain extent, all that is left is admiration and worship!